Insulin Metabolism May Affect Life Span via Effects on Innate Immune Function

Source https://www.fightaging.org/archives/2023/03/insulin-metabolism-may-affect-life-span-via-effects-on-innate-immune-function/

Insulin metabolism is one of the better studied areas of biochemistry in connection with aging, and one of the earliest areas of focus for the aging research community. Dysfunction of insulin metabolism, meaning loss of insulin sensitivity, is characteristic of obesity and the slide into type 2 diabetes, and the manifestations of diabetes in some ways resemble accelerated aging. While one should not consider high levels of a single form of dysfunction to be accelerated aging, since normal aging is a specific mix of various forms of damage and dysfunction, it can be worth bearing in mind that there are mechanistic overlaps between diseases and aging.

In today’s open access paper, researchers connect insulin sensitivity with better function of the <a href="https://en.w…

Source https://www.fightaging.org/archives/2023/03/insulin-metabolism-may-affect-life-span-via-effects-on-innate-immune-function/

Insulin metabolism is one of the better studied areas of biochemistry in connection with aging, and one of the earliest areas of focus for the aging research community. Dysfunction of insulin metabolism, meaning loss of insulin sensitivity, is characteristic of obesity and the slide into type 2 diabetes, and the manifestations of diabetes in some ways resemble accelerated aging. While one should not consider high levels of a single form of dysfunction to be accelerated aging, since normal aging is a specific mix of various forms of damage and dysfunction, it can be worth bearing in mind that there are mechanistic overlaps between diseases and aging.

In today’s open access paper, researchers connect insulin sensitivity with better function of the <a href="https://en.w…

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