Excess Cholesterol Provokes PERK Expression in Vascular Smooth Muscle Cells in Atherosclerosis

Source https://www.fightaging.org/archives/2022/06/excess-cholesterol-provokes-perk-expression-in-vascular-smooth-muscle-cells-in-atherosclerosis/

Atherosclerosis is a condition of localized excesses of cholesterol in blood vessel walls, leading to fatty plaques that narrow and weaken those vessels, ultimately leading to stroke or heart attack. A lot of attention is given to the way in which excess cholesterol induces dysfunction in the macrophage cells responsible for clearing that cholesterol from blood vessel walls, thereby creating a feedback loop in which atherosclerotic plaques grow. Researchers here instead look at the effects of excess cholesterol on <a href="https://en.wikipedia.org/wiki/Smooth_m…

Source https://www.fightaging.org/archives/2022/06/excess-cholesterol-provokes-perk-expression-in-vascular-smooth-muscle-cells-in-atherosclerosis/

Atherosclerosis is a condition of localized excesses of cholesterol in blood vessel walls, leading to fatty plaques that narrow and weaken those vessels, ultimately leading to stroke or heart attack. A lot of attention is given to the way in which excess cholesterol induces dysfunction in the macrophage cells responsible for clearing that cholesterol from blood vessel walls, thereby creating a feedback loop in which atherosclerotic plaques grow. Researchers here instead look at the effects of excess cholesterol on <a href="https://en.wikipedia.org/wiki/Smooth_m…

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